What to Expect When Receiving Mesothelioma Chemotherapy


Receiving mesothelioma chemotherapy, particularly with the combination of Alimta and Cisplatin, involves a structured procedure designed to target the cancer cells effectively while trying to minimize the impact on the patient’s overall health. Here’s what patients can generally expect through the course of this treatment, bearing in mind that individual experiences may vary based on personal health conditions, the specific regimen, and how the body reacts to the drugs.

Before Treatment

  • Folic Acid Supplementation: The week prior to starting the chemotherapy, patients are usually required to take daily doses of folic acid. This is crucial because folic acid can help reduce some of the side effects associated with Alimta.
  • Vitamin B12 Injection: Alongside folic acid, a vitamin B12 injection is administered intramuscularly. This is another measure to counteract potential side effects of the chemotherapy drugs.
  • Corticosteroids: Patients might also be given corticosteroids before, during, and after the chemotherapy sessions. These are used to reduce inflammation and help with managing side effects.

During Treatment

  • IV Infusion: The chemotherapy drugs, Alimta followed by Cisplatin, are administered through an IV infusion. This process is done in cycles, typically every 21 days.
  • Dosage Determination: The exact dosage of each drug is carefully calculated by the doctor, based on various factors including the patient’s overall health, the stage of mesothelioma, and how well the patient’s body can handle the chemotherapy.

After Treatment

  • Recovery Period: After each chemotherapy cycle, patients have a recovery period for the remainder of the 21-day cycle. This time allows the body to recuperate and manage the effects of the drugs.
  • Multiple Cycles: Depending on the specific circumstances of the patient’s health and how well the cancer responds to the treatment, multiple cycles of chemotherapy may be necessary.

Side Effects and Support

While undergoing chemotherapy, patients may experience a range of side effects. Common ones include nausea, vomiting, fatigue, and increased risk of infections due to lowered white blood cell counts. It’s important for patients to communicate any side effects they’re experiencing with their care team, as there are often medications and treatments available to help manage these symptoms.

Moreover, the emotional and mental impact of chemotherapy treatment cannot be understated. Many cancer centers provide support services, including counseling and support groups, to help patients and their families navigate the challenges of cancer treatment.

It’s essential for patients to have open and ongoing conversations with their healthcare team to fully understand their treatment plan, manage expectations, and address any concerns they may have throughout the treatment process.