Epithelial Mesothelioma Critical Facts
Posted on: October 13, 2023 *Updated on: May 27, 2024Epithelial mesothelioma is one of the major histological types of mesothelioma, a rare and aggressive cancer linked primarily to asbestos exposure. Understanding the unique characteristics of epithelial mesothelioma is crucial for patients, healthcare providers, and researchers. Below are some critical facts about this specific type of mesothelioma:
- Predominance: Epithelial mesothelioma, also referred to as epithelioid mesothelioma, is the most common type of mesothelioma. The statistics provided suggest that it accounts for 50% to 70% of all mesothelioma cases.
- Cellular Composition: Epithelial mesothelioma tumors consist predominantly of epithelioid cells, which have a distinct appearance under the microscope. These cells are often cube-shaped or elongated and have a well-defined cell boundary.
- Diagnosis: Each year, doctors diagnose between 1,500 to 2,100 new cases of epithelioid mesothelioma. This suggests the rarity of the disease, but also its prevalence among mesothelioma subtypes.
- Sites of Origin: Mesothelioma can affect various linings within the body. Epithelial mesothelioma is seen in the pleura (lung lining), peritoneum (abdominal lining), pericardium (heart lining), and tunica vaginalis (testicular lining).
- Prognosis: Prognosis refers to the probable outcome or course of a disease. Among the types of mesothelioma, epithelial mesothelioma has a relatively better prognosis. Specifically, patients with epithelial mesothelioma tend to live about six months longer than those diagnosed with other cell types like biphasic or sarcomatoid.
- Treatment Response: The distinct cellular structure and behavior of epithelioid cells mean they typically respond more favorably to aggressive treatments, such as surgery, chemotherapy, and radiation therapy, than other mesothelioma cell types. This responsiveness is a significant reason for the better prognosis associated with epithelial mesothelioma.
- Link to Asbestos: While the specifics were not mentioned in the provided facts, it’s essential to recognize that exposure to asbestos is the primary risk factor for developing mesothelioma, including the epithelial type.
It’s always vital for patients diagnosed with or suspecting they might have epithelial mesothelioma to consult with specialists in the field, ensuring they receive accurate information, a proper diagnosis, and the most effective treatment options available.